Putting the looper into the effects loop of a guitar amp is SO much better than up front. It will be worth finding a small tube amp with an effects loop.
I don't even like having the EDP in front of the amp because I can hear
& feel its effect on the signal, and I don't much care for it. Thus, I
can't & won't comment on your (to my eyes) gigantic effects toolbox, except
to say that it seems to be much easier to model effects & combine them with
a purely digital signal flow than it is to replace a tube amp that sounds,
feels, and responds like a tube amp.