Stephen, Hey man, haven't tried a tamboura out before, but it should be pretty happening, none-the-less. I've used my older E-Bow on lots of differing acoustic instruments, but have had some wild results with a lap dulcimer and a few friends' acoustic guitars. The big difference is in finding the "sweet spot" where the instrument is giving you the most volume when you are activating a string with the E-Bow. You'll find with an acoustic instrument, it isn't going to give you as much volume and that there are a number of different sweet spots on the instrument (this is true for electrics, but again, the volume won't be there unless you're near or over top of a pickup). Try playing just a little above a harmonic node on your instrument, such that if it were a guitar, you'd place/move the E-Bow up to the halfway between the 17th and 18th frets. Yes, I know, the tamboura is a fretless instrument, but you'll get the picture. If my memory servers you're more prone to brushing the strings of this one than you are of actually plucking them, so an E-Bow should give you some pretty happening and slow sounds. Loop on, tap on, gliss out, Lee-ohki.